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Evaluation of an (131)I-labeled HER2-specific single domain antibody fragment for the radiopharmaceutical therapy of HER2-expressing cancers

Radiopharmaceutical therapy (RPT) is an attractive strategy for treatment of disseminated cancers including those overexpressing the HER2 receptor including breast, ovarian and gastroesophageal carcinomas. Single-domain antibody fragments (sdAbs) exemplified by the HER2-targeted VHH_1028 evaluated h...

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Detalles Bibliográficos
Autores principales: Feng, Yutian, Meshaw, Rebecca, McDougald, Darryl, Zhou, Zhengyuan, Zhao, Xiao-Guang, Jannetti, Stephen A., Reiman, Robert E., Pippen, Erica, Marjoram, Robin, Schaal, Jeffrey L., Vaidyanathan, Ganesan, Zalutsky, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864007/
https://www.ncbi.nlm.nih.gov/pubmed/35194100
http://dx.doi.org/10.1038/s41598-022-07006-9