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Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis

Tumor-associated macrophages have emerged as crucial factors for metastases. Microglia are indispensable components of the brain microenvironment and play vital roles in brain metastasis (BM). However, the underlying mechanism of how activated microglia promote brain metastasis of non-small cell lun...

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Detalles Bibliográficos
Autores principales: Jin, Yu, Kang, Yalin, Wang, Minghuan, Wu, Bili, Su, Beibei, Yin, Han, Tang, Yang, Li, Qianxia, Wei, Wenjie, Mei, Qi, Hu, Guangyuan, Lukacs-Kornek, Veronika, Li, Jian, Wu, Kongming, Yuan, Xianglin, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864012/
https://www.ncbi.nlm.nih.gov/pubmed/35194016
http://dx.doi.org/10.1038/s41392-022-00872-9