Quercetin induces pannexin 1 expression via an alternative transcript with a translationally active 5′ leader in rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a deadly cancer of skeletal muscle origin. Pannexin 1 (PANX1) is down-regulated in RMS and increasing its levels drastically inhibits RMS progression. PANX1 upregulation thus represents a prospective new treatment strategy for this malignancy. However, the mechanisms regula...

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Detalles Bibliográficos
Autores principales: Xiang, Xiao, Hoang, Huy-Dung, Gilchrist, Victoria H., Langlois, Stéphanie, Alain, Tommy, Cowan, Kyle N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864035/
https://www.ncbi.nlm.nih.gov/pubmed/35194046
http://dx.doi.org/10.1038/s41389-022-00384-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864035/
https://www.ncbi.nlm.nih.gov/pubmed/35194046
http://dx.doi.org/10.1038/s41389-022-00384-9

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