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Essential Functions of MLL1 and MLL2 in Retinal Development and Cone Cell Maintenance

MLL1 (KMT2A) and MLL2 (KMT2B) are homologous members of the mixed-lineage leukemia (MLL) family of histone methyltransferases involved in epigenomic transcriptional regulation. Their sequence variants have been associated with neurological and psychological disorders, but little is known about their...

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Detalles Bibliográficos
Autores principales: Sun, Chi, Zhang, Xiaodong, Ruzycki, Philip A., Chen, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864151/
https://www.ncbi.nlm.nih.gov/pubmed/35223853
http://dx.doi.org/10.3389/fcell.2022.829536