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Gene Therapy Advances: A Meta-Analysis of AAV Usage in Clinical Settings

Adeno-associated viruses (AAVs) are the safest and most effective gene delivery vehicles to drive long-term transgene expression in gene therapy. While animal studies have shown promising results, the translatability of AAVs into clinical settings has been partly limited due to their restricted gene...

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Detalles Bibliográficos
Autores principales: Au, Hau Kiu Edna, Isalan, Mark, Mielcarek, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864161/
https://www.ncbi.nlm.nih.gov/pubmed/35223884
http://dx.doi.org/10.3389/fmed.2021.809118