Functional Effects of ARV-1502 Analogs Against Bacterial Hsp70 and Implications for Antimicrobial Activity

The antimicrobial peptide (AMP) ARV-1502 was designed based on naturally occurring short proline-rich AMPs, including pyrrhocoricin and drosocin. Identification of chaperone DnaK as a therapeutic target in Escherichia coli triggered intense research on the ligand-DnaK-interactions using fluorescence...

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Detalles Bibliográficos
Autores principales: Brakel, Alexandra, Kolano, Lisa, Kraus, Carl N., Otvos, Laszlo, Hoffmann, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864165/
https://www.ncbi.nlm.nih.gov/pubmed/35223768
http://dx.doi.org/10.3389/fchem.2022.798006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864165/
https://www.ncbi.nlm.nih.gov/pubmed/35223768
http://dx.doi.org/10.3389/fchem.2022.798006

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