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Neoantigen Quantity and Quality in Relation to Pancreatic Cancer Survival

INTRODUCTION: Factors underlying antitumor immunity in pancreatic cancer (PC) are poorly understood. We hypothesized that not neoantigen quantity, but quality, is related to immune cell infiltration and survival. METHODOLOGY: We performed genomic and transcriptomic profiling of paired normal, tumor...

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Detalles Bibliográficos
Autores principales: Levink, Iris J. M., Brosens, Lodewijk A. A., Rensen, Sander S., Aberle, Merel R., Olde Damink, Steven S. W., Cahen, Djuna L., Buschow, Sonja I., Fuhler, Gwenny M., Peppelenbosch, Maikel P., Bruno, Marco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864178/
https://www.ncbi.nlm.nih.gov/pubmed/35223878
http://dx.doi.org/10.3389/fmed.2021.751110