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scDPN for High-throughput Single-cell CNV Detection to Uncover Clonal Evolution During HCC Recurrence
Single-cell genomics provides substantial resources for dissecting cellular heterogeneity and cancer evolution. Unfortunately, classical DNA amplification-based methods have low throughput and introduce coverage bias during sample preamplification. We developed a single-cell DNA library preparation...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864190/ https://www.ncbi.nlm.nih.gov/pubmed/34280548 http://dx.doi.org/10.1016/j.gpb.2021.03.008 |