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scDPN for High-throughput Single-cell CNV Detection to Uncover Clonal Evolution During HCC Recurrence

Single-cell genomics provides substantial resources for dissecting cellular heterogeneity and cancer evolution. Unfortunately, classical DNA amplification-based methods have low throughput and introduce coverage bias during sample preamplification. We developed a single-cell DNA library preparation...

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Detalles Bibliográficos
Autores principales:	Wu, Liang, Jiang, Miaomiao, Wang, Yuzhou, Zhou, Biaofeng, Sun, Yunfan, Zhou, Kaiqian, Xie, Jiarui, Zhong, Yu, Zhao, Zhikun, Dean, Michael, Hou, Yong, Liu, Shiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864190/ https://www.ncbi.nlm.nih.gov/pubmed/34280548 http://dx.doi.org/10.1016/j.gpb.2021.03.008

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