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Polar Gini Curve: A Technique to Discover Gene Expression Spatial Patterns from Single-cell RNA-seq Data

In this work, we describe the development of Polar Gini Curve, a method for characterizing cluster markers by analyzing single-cell RNA sequencing (scRNA-seq) data. Polar Gini Curve combines the gene expression and the 2D coordinates (“spatial”) information to detect patterns of uniformity in any cl...

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Detalles Bibliográficos
Autores principales: Nguyen, Thanh Minh, Jeevan, Jacob John, Xu, Nuo, Chen, Jake Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864247/
https://www.ncbi.nlm.nih.gov/pubmed/34958962
http://dx.doi.org/10.1016/j.gpb.2020.09.006