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Polar Gini Curve: A Technique to Discover Gene Expression Spatial Patterns from Single-cell RNA-seq Data
In this work, we describe the development of Polar Gini Curve, a method for characterizing cluster markers by analyzing single-cell RNA sequencing (scRNA-seq) data. Polar Gini Curve combines the gene expression and the 2D coordinates (“spatial”) information to detect patterns of uniformity in any cl...
Autores principales: | Nguyen, Thanh Minh, Jeevan, Jacob John, Xu, Nuo, Chen, Jake Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864247/ https://www.ncbi.nlm.nih.gov/pubmed/34958962 http://dx.doi.org/10.1016/j.gpb.2020.09.006 |
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