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Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes

The human retinal pigment epithelial RPE-1 cell line immortalized with hTERT retains a stable karyotype with a modal chromosome number of 46 and has been widely used to study physiological events in human cell culture systems. To facilitate inducible knock-out or knock-in experiments in this cell li...

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Detalles Bibliográficos
Autores principales: Hindul, Naushin L., Jhita, Amarjot, Oprea, Daiana G., Hussain, Tasnim Alamgir, Gonchar, Oksana, Campillo, Miguel Angel Muro, O'Regan, Laura, Kanemaki, Masato T., Fry, Andrew M., Hirota, Kouji, Tanaka, Kayoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864296/
https://www.ncbi.nlm.nih.gov/pubmed/35067715
http://dx.doi.org/10.1242/bio.059056