Loss of SPTBN1 Suppresses Autophagy Via SETD7-mediated YAP Methylation in Hepatocellular Carcinoma Initiation and Development

BACKGROUND & AIMS: Loss of Spectrin beta, non-erythrocytic 1 (SPTBN1) plays an important role in the carcinogenesis of hepatocellular carcinoma (HCC); however, the mechanisms underlying its involvement remain poorly understood. Defects in autophagy contribute to hepatic tumor formation. Hence, i...

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Detalles Bibliográficos
Autores principales: Chen, Shuyi, Wu, Huijie, Wang, Zhengyang, Jia, Mengping, Guo, Jieyu, Jin, Jiayu, Li, Xiaobo, Meng, Dan, Lin, Ling, He, Aiwu Ruth, Zhou, Ping, Zhi, Xiuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864474/
https://www.ncbi.nlm.nih.gov/pubmed/34737104
http://dx.doi.org/10.1016/j.jcmgh.2021.10.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864474/
https://www.ncbi.nlm.nih.gov/pubmed/34737104
http://dx.doi.org/10.1016/j.jcmgh.2021.10.012

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