Cargando…

Ophiopogonin-B targets PTP1B to inhibit the malignant progression of hepatocellular carcinoma by regulating the PI3K/AKT and AMPK signaling pathways

Ophiopogonin-B (OP-B) is a bioactive component from the root of Ophiopogon japonicus, which can exert anticancer effects on multiple malignant tumors. The present study aimed to uncover the effects of OP-B on hepatocellular carcinoma (HCC) and the underlying mechanisms. An HCC-xenografted mouse mode...

Descripción completa

Detalles Bibliográficos
Autores principales: Yuan, Fang, Gao, Qian, Tang, Hailin, Shi, Jun, Zhou, Yiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864608/
https://www.ncbi.nlm.nih.gov/pubmed/35169857
http://dx.doi.org/10.3892/mmr.2022.12638