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Ophiopogonin-B targets PTP1B to inhibit the malignant progression of hepatocellular carcinoma by regulating the PI3K/AKT and AMPK signaling pathways
Ophiopogonin-B (OP-B) is a bioactive component from the root of Ophiopogon japonicus, which can exert anticancer effects on multiple malignant tumors. The present study aimed to uncover the effects of OP-B on hepatocellular carcinoma (HCC) and the underlying mechanisms. An HCC-xenografted mouse mode...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864608/ https://www.ncbi.nlm.nih.gov/pubmed/35169857 http://dx.doi.org/10.3892/mmr.2022.12638 |