Gata2 +9.5 enhancer regulates adult hematopoietic stem cell self-renewal and T-cell development

Mammalian GATA2 gene encodes a dual zinc finger transcription factor, which is essential for hematopoietic stem cell (HSC) generation in the aorta, gonad, mesonephros (AGM) region, HSC self-renewal, and specification of progenitor cell fates. Previously, we demonstrated that Gata2 expression in AGM...

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Detalles Bibliográficos
Autores principales: You, Xiaona, Zhou, Yun, Chang, Yuan-I, Kong, Guangyao, Ranheim, Erik A., Johnson, Kirby D., Soukup, Alexandra A., Bresnick, Emery H., Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Stimulus Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864660/
https://www.ncbi.nlm.nih.gov/pubmed/34516632
http://dx.doi.org/10.1182/bloodadvances.2021004311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864660/
https://www.ncbi.nlm.nih.gov/pubmed/34516632
http://dx.doi.org/10.1182/bloodadvances.2021004311

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