Unrelated donor α/β T cell– and B cell–depleted HSCT for the treatment of pediatric acute leukemia

Unrelated donor (URD) hematopoietic stem cell transplant (HSCT) is associated with an increased risk of severe graft-versus-host disease (GVHD). TCRαβ/CD19 depletion may reduce this risk, whereas maintaining graft-versus-leukemia. Outcome data with TCRαβ/CD19 depletion generally describe haploidenti...

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Detalles Bibliográficos
Autores principales: Leahy, Allison Barz, Li, Yimei, Talano, Julie-An, Elgarten, Caitlin W., Seif, Alix E., Wang, Yongping, Johnson, Bryon, Monos, Dimitri S., Kadauke, Stephan, Olson, Timothy S., Freedman, Jason, Wray, Lisa, Grupp, Stephan A., Bunin, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Clinical Trials and Observations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864664/
https://www.ncbi.nlm.nih.gov/pubmed/34872106
http://dx.doi.org/10.1182/bloodadvances.2021005492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864664/
https://www.ncbi.nlm.nih.gov/pubmed/34872106
http://dx.doi.org/10.1182/bloodadvances.2021005492

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