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Highly regioselective and diastereodivergent aminomethylative annulation of dienyl alcohols enabled by a hydrogen-bonding assisting effect

A ligand-controlled palladium-catalyzed highly regioselective and diastereodivergent aminomethylative annulation of dienyl alcohols with aminals has been established, which allows for producing either cis- or trans-disubstituted isochromans in good yields with complete regioselectivity and good to e...

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Detalles Bibliográficos
Autores principales: Huang, Yao, Zou, Suchen, Yu, Bangkui, Yan, Xuyang, Liu, Song, Huang, Hanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864680/
https://www.ncbi.nlm.nih.gov/pubmed/35310502
http://dx.doi.org/10.1039/d1sc06479g