The importance of the compact disordered state in the fuzzy interactions between intrinsically disordered proteins

The intrinsically disordered C-terminal domain (CTD) of protein 4.1G is able to specifically bind a 26-residue intrinsically disordered region of NuMA, forming a dynamic fuzzy complex. As one of a few cases of extremely fuzzy interactions between two intrinsically disordered proteins/regions (IDPs/I...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Wu, Shaowen, Wang, Dongdong, Song, Xingyu, Yang, Maohua, Zhang, Wolun, Huang, Shaohui, Weng, Jingwei, Liu, Zhijun, Wang, Wenning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864705/
https://www.ncbi.nlm.nih.gov/pubmed/35310482
http://dx.doi.org/10.1039/d1sc06825c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864705/
https://www.ncbi.nlm.nih.gov/pubmed/35310482
http://dx.doi.org/10.1039/d1sc06825c

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