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Enhancing proline-rich antimicrobial peptide action by homodimerization: influence of bifunctional linker

Antimicrobial peptides (AMPs) are host defense peptides, and unlike conventional antibiotics, they possess potent broad spectrum activities and, induce little or no antimicrobial resistance. They are attractive lead molecules for rational development to improve their therapeutic index. Our current s...

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Detalles Bibliográficos
Autores principales: Li, Wenyi, Lin, Feng, Hung, Andrew, Barlow, Anders, Sani, Marc-Antoine, Paolini, Rita, Singleton, William, Holden, James, Hossain, Mohammed Akhter, Separovic, Frances, O'Brien-Simpson, Neil M., Wade, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864714/
https://www.ncbi.nlm.nih.gov/pubmed/35310489
http://dx.doi.org/10.1039/d1sc05662j