Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates

The introduction of glycoconjugate vaccines marks an important point in the fight against various infectious diseases. The covalent conjugation of relevant polysaccharide antigens to immunogenic carrier proteins enables the induction of a long-lasting and robust IgG antibody response, which is not o...

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Detalles Bibliográficos
Autores principales: Carboni, Filippo, Kitowski, Annabel, Sorieul, Charlotte, Veggi, Daniele, Marques, Marta C., Oldrini, Davide, Balducci, Evita, Brogioni, Barbara, Del Bino, Linda, Corrado, Alessio, Angiolini, Francesca, Dello Iacono, Lucia, Margarit, Immaculada, Romano, Maria Rosaria, Bernardes, Gonçalo J. L., Adamo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864718/
https://www.ncbi.nlm.nih.gov/pubmed/35310500
http://dx.doi.org/10.1039/d1sc01928g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864718/
https://www.ncbi.nlm.nih.gov/pubmed/35310500
http://dx.doi.org/10.1039/d1sc01928g

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