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High-affinity ZnT8 Autoantibodies by Electrochemiluminescence Assay Improve Risk Prediction for Type 1 Diabetes

CONTEXT: Single ZnT8 autoantibody (ZnT8A) positivity by standard radiobinding assay (RBA) is commonly seen in nondiabetes population-based screening and the risk of progression to type 1 diabetes (T1D) in subjects with single ZnT8A is unknown. OBJECTIVE: Identify the risk of progression to T1D in in...

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Detalles Bibliográficos
Autores principales: Jia, Xiaofan, He, Ling, Miao, Dongmei, Waugh, Kathleen, Rasmussen, Cristy Geno, Dong, Fran, Steck, Andrea K, Rewers, Marian, Yu, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864749/
https://www.ncbi.nlm.nih.gov/pubmed/34343303
http://dx.doi.org/10.1210/clinem/dgab575