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Metformin Downregulates the Expression of Epidermal Growth Factor Receptor Independent of Lowering Blood Glucose in Oral Squamous Cell Carcinoma

PURPOSE: Type 2 diabetes mellitus (T2DM) is among the risk factors for the occurrence and development of cancer. Metformin is a potential anticancer drug. Epidermal growth factor receptor (EGFR) plays an important role in the progression of oral squamous cell carcinoma(OSCC), but the relationship be...

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Detalles Bibliográficos
Autores principales: Wang, Wei-Ming, Yang, Si-Si, Shao, Shu-Hui, Nie, Huan-Quan, Zhang, Jing, Su, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864766/
https://www.ncbi.nlm.nih.gov/pubmed/35222283
http://dx.doi.org/10.3389/fendo.2022.828608