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Attenuates of NAD(+) impair BMSC osteogenesis and fracture repair through OXPHOS

BACKGROUND: Controlling the adipo-osteogenic lineage commitment of bone marrow mesenchymal stem cell (BMSC) in favor of osteogenesis is considered a promising approach for bone regeneration and repair. Accumulating evidence indicates that oxidative phosphorylation (OXPHOS) is involved in regulating...

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Detalles Bibliográficos
Autores principales: Li, Boer, Shi, Yu, Liu, Mengyu, Wu, Fanzi, Hu, Xuchen, Yu, Fanyuan, Wang, Chenglin, Ye, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864833/
https://www.ncbi.nlm.nih.gov/pubmed/35193674
http://dx.doi.org/10.1186/s13287-022-02748-9