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LncRNA HOTAIR facilitates high glucose-induced mesangial cell proliferation, fibrosis and oxidative stress in diabetic nephropathy via regulating miR-147a/WNT2B axis

BACKGROUND: Long non-coding RNAs (lncRNAs) have been shown to be involved in the regulation of many disease progression. However, the role of lncRNA HOX transcript antisense RNA (HOTAIR) in diabetic nephropathy (DN) remains unclear. METHODS: High glucose (HG)-induced human mesangial cells (HMC) was...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Wang, Wei, HuangFu, Weizhong, Liu, Zhonghua, Zhao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864868/
https://www.ncbi.nlm.nih.gov/pubmed/35193668
http://dx.doi.org/10.1186/s13098-022-00802-3