Structural insights into inhibition of PRRSV Nsp4 revealed by structure-based virtual screening, molecular dynamics, and MM-PBSA studies

BACKGROUND: Porcine reproductive and respiratory syndrome respiratory sickness in weaned and growing pigs, as well as sow reproductive failure, and its infection is regarded as one of the most serious swine illnesses worldwide. Given the current lack of an effective treatment, in this study, we iden...

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Detalles Bibliográficos
Autores principales: Pathak, Rajesh Kumar, Seo, Young-Jun, Kim, Jun-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864930/
https://www.ncbi.nlm.nih.gov/pubmed/35193698
http://dx.doi.org/10.1186/s13036-022-00284-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864930/
https://www.ncbi.nlm.nih.gov/pubmed/35193698
http://dx.doi.org/10.1186/s13036-022-00284-x

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