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Effect of RecA inactivation and detoxification systems on the evolution of ciprofloxacin resistance in Escherichia coli

BACKGROUND: Suppression of SOS response and overproduction of reactive oxygen species (ROS) through detoxification system suppression enhance the activity of fluoroquinolones. OBJECTIVES: To evaluate the role of both systems in the evolution of resistance to ciprofloxacin in an isogenic model of Esc...

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Detalles Bibliográficos
Autores principales: Diaz-Diaz, S, Recacha, E, García-Duque, A, Docobo-Pérez, F, Blázquez, J, Pascual, A, Rodríguez-Martínez, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864997/
https://www.ncbi.nlm.nih.gov/pubmed/34878138
http://dx.doi.org/10.1093/jac/dkab445