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Effect of RecA inactivation and detoxification systems on the evolution of ciprofloxacin resistance in Escherichia coli
BACKGROUND: Suppression of SOS response and overproduction of reactive oxygen species (ROS) through detoxification system suppression enhance the activity of fluoroquinolones. OBJECTIVES: To evaluate the role of both systems in the evolution of resistance to ciprofloxacin in an isogenic model of Esc...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864997/ https://www.ncbi.nlm.nih.gov/pubmed/34878138 http://dx.doi.org/10.1093/jac/dkab445 |