Genotypic, proteomic, and phenotypic approaches to decipher the response to caspofungin and calcineurin inhibitors in clinical isolates of echinocandin-resistant Candida glabrata

BACKGROUND: Echinocandin resistance represents a great concern, as these drugs are recommended as first-line therapy for invasive candidiasis. Echinocandin resistance is conferred by mutations in FKS genes. Nevertheless, pathways are crucial for enabling tolerance, evolution, and maintenance of resi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ceballos-Garzon, Andres, Monteoliva, Lucia, Gil, Concha, Alvarez-Moreno, Carlos, Vega-Vela, Nelson E, Engelthaler, David M, Bowers, Jolene, Le Pape, Patrice, Parra-Giraldo, Claudia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865013/
https://www.ncbi.nlm.nih.gov/pubmed/34893830
http://dx.doi.org/10.1093/jac/dkab454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865013/
https://www.ncbi.nlm.nih.gov/pubmed/34893830
http://dx.doi.org/10.1093/jac/dkab454

Ejemplares similares