Genotypic, proteomic, and phenotypic approaches to decipher the response to caspofungin and calcineurin inhibitors in clinical isolates of echinocandin-resistant Candida glabrata

BACKGROUND: Echinocandin resistance represents a great concern, as these drugs are recommended as first-line therapy for invasive candidiasis. Echinocandin resistance is conferred by mutations in FKS genes. Nevertheless, pathways are crucial for enabling tolerance, evolution, and maintenance of resi...

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Detalles Bibliográficos
Autores principales: Ceballos-Garzon, Andres, Monteoliva, Lucia, Gil, Concha, Alvarez-Moreno, Carlos, Vega-Vela, Nelson E, Engelthaler, David M, Bowers, Jolene, Le Pape, Patrice, Parra-Giraldo, Claudia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865013/
https://www.ncbi.nlm.nih.gov/pubmed/34893830
http://dx.doi.org/10.1093/jac/dkab454

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