Isocoumarins: a new class of selective carbonic anhydrase IX and XII inhibitors

Isocoumarins, isomeric to comarins which act as effective carbonic anhydrase (CA, EC 4.2.1.1) inhibitors, were investigated for the first time as inhibitors of this enzyme. A series of 3-substituted and 3,4-disubstituted isocoumarins incorporating phenylhydrazone, 1-phenyl-pyrazole and pyrazolo-subs...

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Detalles Bibliográficos
Autores principales: Onyılmaz, Mehmet, Koca, Murat, Bonardi, Alessandro, Degirmenci, Mustafa, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865125/
https://www.ncbi.nlm.nih.gov/pubmed/35188025
http://dx.doi.org/10.1080/14756366.2022.2041630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865125/
https://www.ncbi.nlm.nih.gov/pubmed/35188025
http://dx.doi.org/10.1080/14756366.2022.2041630

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