LY395756 promotes NR2B expression via activation of AKT/CREB signaling in the juvenile methylazoxymethanol mice model of schizophrenia

INTRODUCTION: Synaptic N‐methyl‐d‐aspartate receptor subtype 2B(NR2B) is significantly reduced in prefrontal cortex (PFC) in the neurodevelopmental methylazoxymethanol (MAM) model of schizophrenia (SCZ). Recent research has shown that LY395756 can effectively restore NR2B levels and improve cognitiv...

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Detalles Bibliográficos
Autores principales: Li, Meng‐lin, Peng, Yuan, An, Ying, Li, Guo‐yan, Lan, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865150/
https://www.ncbi.nlm.nih.gov/pubmed/35025141
http://dx.doi.org/10.1002/brb3.2466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865150/
https://www.ncbi.nlm.nih.gov/pubmed/35025141
http://dx.doi.org/10.1002/brb3.2466

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