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ROS-Induced DCTPP1 Upregulation Contributes to Cisplatin Resistance in Ovarian Cancer

Cisplatin resistance hinders the improvement of the prognosis of patients with ovarian cancer. Cisplatin induces cancer cell apoptosis by inducing reactive oxygen species (ROS). dCTP pyrophosphatase 1 (DCTPP1) is a newly discovered dNTP pyrophosphatase. This study aimed to identify the role of DCTPP...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Chen, Peishi, Chen, Xueping, Gong, Daoyuan, Wu, Yingsong, Huang, Liping, Chen, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865183/
https://www.ncbi.nlm.nih.gov/pubmed/35223993
http://dx.doi.org/10.3389/fmolb.2022.838006