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Toll-Like Receptor 3 Is Critical to the Pancreatic Islet Milieu That Is Required for Coxsackievirus B4–Induced Type 1 Diabetes in Female Nonobese Diabetic Mice

OBJECTIVE: Genetic and environmental influences play a role as triggers of type 1 diabetes mellitus (T1DM). Female nonobese diabetic (NOD) mice are useful for studying T1DM as they spontaneously develop T1DM, which can be accelerated by some viruses. Toll-like receptor 3 (TLR3) is believed to play a...

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Detalles Bibliográficos
Autores principales: Benner, Sarah E., Walter, Debra L., Thuma, Jean R., Courreges, Maria, James, Calvin B. L., Schwartz, Frank L., McCall, Kelly D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865205/
https://www.ncbi.nlm.nih.gov/pubmed/35195595
http://dx.doi.org/10.1097/MPA.0000000000001960