The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma

The small non-coding VTRNA1-1 (vault RNA 1–1) is known to confer resistance to apoptosis in several malignant cell lines and to also modulate the macroautophagic/autophagic flux in hepatocytes, thus highlighting its pro-survival role. Here we describe a new function of VTRNA1-1 in regulating in vitr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferro, Iolanda, Gavini, Jacopo, Gallo, Stefano, Bracher, Lisamaria, Landolfo, Marc, Candinas, Daniel, Stroka, Deborah M., Polacek, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865259/
https://www.ncbi.nlm.nih.gov/pubmed/33960270
http://dx.doi.org/10.1080/15548627.2021.1922983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865259/
https://www.ncbi.nlm.nih.gov/pubmed/33960270
http://dx.doi.org/10.1080/15548627.2021.1922983

Ejemplares similares