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The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma

The small non-coding VTRNA1-1 (vault RNA 1–1) is known to confer resistance to apoptosis in several malignant cell lines and to also modulate the macroautophagic/autophagic flux in hepatocytes, thus highlighting its pro-survival role. Here we describe a new function of VTRNA1-1 in regulating in vitr...

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Detalles Bibliográficos
Autores principales:	Ferro, Iolanda, Gavini, Jacopo, Gallo, Stefano, Bracher, Lisamaria, Landolfo, Marc, Candinas, Daniel, Stroka, Deborah M., Polacek, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865259/ https://www.ncbi.nlm.nih.gov/pubmed/33960270 http://dx.doi.org/10.1080/15548627.2021.1922983

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