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Identification of Recurrent Insertions and Deletions in Exon 18 and 19 of Human Epidermal Growth Factor Receptor 2 as Potential Drivers in Non–Small-Cell Lung Cancer and Other Cancer Types

PURPOSE: Human epidermal growth factor receptor 2 (HER2) belongs to the same family as epidermal growth factor receptor (EGFR) and is known as an important cancer driver gene. Insertions and deletions (indels) are frequent driver mutations in both EGFR and HER2. The most common HER2 indels are the e...

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Detalles Bibliográficos
Autores principales: Yin, Yan, Song, Lijie, Shi, Dongsheng, Liu, Bin, Li, Xiangke, Yang, Minjie, Liu, Bihao, Wang, Dejuan, Qin, Jianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865527/
https://www.ncbi.nlm.nih.gov/pubmed/35171661
http://dx.doi.org/10.1200/PO.21.00325