Genome-Wide CRISPR-Cas9 Screen Does Not Identify Host Factors Modulating Streptococcus agalactiae β-Hemolysin/Cytolysin-Induced Cell Death

Pore-forming toxins (PFTs) are commonly produced by pathogenic bacteria, and understanding them is key to the development of virulence-targeted therapies. Streptococcus agalactiae, or group B Streptococcus (GBS), produces several factors that enhance its pathogenicity, including the PFT β-hemolysin/...

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Detalles Bibliográficos
Autores principales: Shahi, Ifrah, Llaneras, Cristina N., Perelman, Sofya S., Torres, Victor J., Ratner, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865549/
https://www.ncbi.nlm.nih.gov/pubmed/35196804
http://dx.doi.org/10.1128/spectrum.02186-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865549/
https://www.ncbi.nlm.nih.gov/pubmed/35196804
http://dx.doi.org/10.1128/spectrum.02186-21

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