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High-Throughput Screening of a Promoter Library Reveals New Persister Mechanisms in Escherichia Coli

Persister cells are a small subpopulation of phenotypic variants that survive high concentrations of bactericidal antibiotics. Their survival mechanisms are not heritable and can be formed stochastically or triggered by environmental stresses such as antibiotic treatment. In this study, high-through...

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Detalles Bibliográficos
Autores principales: Mohiuddin, Sayed Golam, Massahi, Aslan, Orman, Mehmet A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865558/
https://www.ncbi.nlm.nih.gov/pubmed/35196813
http://dx.doi.org/10.1128/spectrum.02253-21