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AFF4 Predicts the Prognosis of Colorectal Cancer Patients and Suppresses Colorectal Cancer Metastasis via Promoting CDH1 Expression

INTRODUCTION: AF4/FMR2 family member 4 (AFF4) is a core component of super elongation complex (SEC) and regulates the transcription elongation of many genes. AFF4 depletion or amplification is associated with multiple cancers, but its role in colorectal cancer (CRC) has not been investigated so far....

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Detalles Bibliográficos
Autores principales: Fang, Yi, Cao, Hua, Gong, Xiaoyong, Chen, Yanqing, Zhuang, Yugang, Zhou, Shuqin, Chen, Yuanzhuo, Jiang, Yimei, Ji, Xiaopin, Peng, Hu, Jing, Xiaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865618/
https://www.ncbi.nlm.nih.gov/pubmed/35223479
http://dx.doi.org/10.3389/fonc.2022.797392