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A genetic screen in C. elegans reveals roles for KIN17 and PRCC in maintaining 5’ splice site identity

Pre-mRNA splicing is an essential step of eukaryotic gene expression carried out by a series of dynamic macromolecular protein/RNA complexes, known collectively and individually as the spliceosome. This series of spliceosomal complexes define, assemble on, and catalyze the removal of introns. Molecu...

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Detalles Bibliográficos
Autores principales: Suzuki, Jessie M. N. G. L., Osterhoudt, Kenneth, Cartwright-Acar, Catiana H., Gomez, Destiny R., Katzman, Sol, Zahler, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865678/
https://www.ncbi.nlm.nih.gov/pubmed/35143478
http://dx.doi.org/10.1371/journal.pgen.1010028