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A genetic screen in C. elegans reveals roles for KIN17 and PRCC in maintaining 5’ splice site identity
Pre-mRNA splicing is an essential step of eukaryotic gene expression carried out by a series of dynamic macromolecular protein/RNA complexes, known collectively and individually as the spliceosome. This series of spliceosomal complexes define, assemble on, and catalyze the removal of introns. Molecu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865678/ https://www.ncbi.nlm.nih.gov/pubmed/35143478 http://dx.doi.org/10.1371/journal.pgen.1010028 |