Slow nucleosome dynamics set the transcriptional speed limit and induce RNA polymerase II traffic jams and bursts

Nucleosomes are recognized as key regulators of transcription. However, the relationship between slow nucleosome unwrapping dynamics and bulk transcriptional properties has not been thoroughly explored. Here, an agent-based model that we call the dynamic defect Totally Asymmetric Simple Exclusion Pr...

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Detalles Bibliográficos
Autores principales: Mines, Robert C., Lipniacki, Tomasz, Shen, Xiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865691/
https://www.ncbi.nlm.nih.gov/pubmed/35143483
http://dx.doi.org/10.1371/journal.pcbi.1009811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865691/
https://www.ncbi.nlm.nih.gov/pubmed/35143483
http://dx.doi.org/10.1371/journal.pcbi.1009811

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