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Machine learning modeling of family wide enzyme-substrate specificity screens
Biocatalysis is a promising approach to sustainably synthesize pharmaceuticals, complex natural products, and commodity chemicals at scale. However, the adoption of biocatalysis is limited by our ability to select enzymes that will catalyze their natural chemical transformation on non-natural substr...
Autores principales: | Goldman, Samuel, Das, Ria, Yang, Kevin K., Coley, Connor W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865696/ https://www.ncbi.nlm.nih.gov/pubmed/35143485 http://dx.doi.org/10.1371/journal.pcbi.1009853 |
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