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Follicular Helper–like T Cells in the Lung Highlight a Novel Role of B Cells in Sarcoidosis

RATIONALE: Pulmonary sarcoidosis is generally presumed to be a T-helper cell type 1– and macrophage-driven disease. However, mouse models have recently revealed that chronically inflamed lung tissue can also comprise T follicular helper (Tfh)-like cells and represents a site of active T-cell/B-cell...

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Detalles Bibliográficos
Autores principales: Bauer, Laura, Müller, Lisa Jasmin, Volkers, Sarah M., Heinrich, Frederik, Mashreghi, Mir-Farzin, Ruppert, Clemens, Sander, Leif E., Hutloff, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865704/
https://www.ncbi.nlm.nih.gov/pubmed/34534436
http://dx.doi.org/10.1164/rccm.202012-4423OC