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Rosuvastatin exerts cardioprotective effect in lipopolysaccharide-mediated injury of cardiomyocytes in an MG53-dependent manner

BACKGROUND: Myocarditis is a cardiomyopathy associated with the inflammatory response. Rosuvastatin (RS) demonstrates cardioprotective effect in the clinical setting, although its cellular and molecular mechanisms in ameliorating myocarditis are largely unknown. MG53 (muscle-specific E3 ligase Mitsu...

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Detalles Bibliográficos
Autores principales: Zhuang, Jiawei, Cheng, Gangyi, Huang, Jian, Guo, Hongwei, Lai, Yiquan, Wang, Jiamao, Shan, Zhonggui, Zheng, Shaoyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865731/
https://www.ncbi.nlm.nih.gov/pubmed/35196979
http://dx.doi.org/10.1186/s12872-022-02458-3