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Pharmacokinetic Drug Interaction Between Amlodipine and Tadalafil: An Open-Label, Randomized, Multiple-Dose Crossover Study in Healthy Male Volunteers

PURPOSE: The combined administration of tadalafil, a phosphodiesterase-5 inhibitor, and amlodipine, a calcium channel blocker, can be a promising therapeutic option for hypertension patients with erectile dysfunction. This study aimed to examine the pharmacokinetic drug interaction between tadalafil...

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Detalles Bibliográficos
Autores principales: Kim, Hyungsub, Lee, Shi Hyang, Jung, Jina, Hong, Sunghee, Lim, Hyeong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865872/
https://www.ncbi.nlm.nih.gov/pubmed/35221673
http://dx.doi.org/10.2147/DDDT.S348897