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PcrA Dissociates RecA Filaments and the SsbA and RecO Mediators Counterbalance Such Activity

PcrA depletion is lethal in wild-type Bacillus subtilis cells. The PcrA DNA helicase contributes to unwinding RNA from the template strand, backtracking the RNA polymerase, rescuing replication-transcription conflicts, and disassembling RecA from single-stranded DNA (ssDNA) by poorly understood mech...

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Detalles Bibliográficos
Autores principales: Carrasco, Begoña, Moreno-del Álamo, María, Torres, Rubén, Alonso, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865920/
https://www.ncbi.nlm.nih.gov/pubmed/35223992
http://dx.doi.org/10.3389/fmolb.2022.836211