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Macrophage IL-1β promotes arteriogenesis by autocrine STAT3- and NF-κB-mediated transcription of pro-angiogenic VEGF-A

Peripheral artery disease (PAD) leads to considerable morbidity, yet strategies for therapeutic angiogenesis fall short of being impactful. Inflammatory macrophage subsets play an important role in orchestrating post-developmental angiogenesis, but the underlying mechanisms are unclear. Here, we fin...

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Detalles Bibliográficos
Autores principales: Mantsounga, Chris S., Lee, Cadence, Neverson, Jade, Sharma, Sheila, Healy, Abigail, Berus, Joshua M., Parry, Crystal, Ceneri, Nicolle M., López-Giráldez, Francesc, Chun, Hyung J., Lu, Qing, Sellke, Frank, Choudhary, Gaurav, Morrison, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865931/
https://www.ncbi.nlm.nih.gov/pubmed/35108537
http://dx.doi.org/10.1016/j.celrep.2022.110309