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Boldine, an Alkaloid from Peumus boldus Molina, Induces Endothelium-Dependent Vasodilation in the Perfused Rat Kidney: Involvement of Nitric Oxide and Small-Conductance Ca(2+)-Activated K(+) Channel

Boldine, 2,9-dihydroxy-1,10-dimethoxyaporphine, is the main alkaloid found in the leaves and bark of Peumus boldus Molina. In recent years, boldine has demonstrated several pharmacological properties that benefit endothelial function, blood pressure control, and reduce damage in kidney diseases. How...

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Detalles Bibliográficos
Autores principales: de Souza, Priscila, da Silva, Rita de Cássia Vilhena, da Silva, Luisa Mota, Steimbach, Viviane Miranda Bispo, Moreno, Karyne Garcia Tafarelo, Gasparotto Junior, Arquimedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865971/
https://www.ncbi.nlm.nih.gov/pubmed/35222671
http://dx.doi.org/10.1155/2022/4560607