Occludin Promotes Adhesion of CD8(+) T Cells and Melanocytes in Vitiligo via the HIF-1α Signaling Pathway

Loss of melanocytes induced by activated CD8(+) T cells is the pathological hallmark of vitiligo. Melanocyte-specific CD8(+) T cells are recruited to the skin via chemokines, thereby releasing perforin, granzyme, and other cytotoxic substances that destroy the melanocytes. However, the mechanism of...

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Detalles Bibliográficos
Autores principales: Zou, Puyu, Xiao, Yangfan, Deng, Qiancheng, Shi, Yaqian, You, Ruixuan, Pi, Zixin, Liu, Jiani, Zhan, Yi, Zeng, Qinghai, Zeng, Zhuotong, Xiao, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865978/
https://www.ncbi.nlm.nih.gov/pubmed/35222802
http://dx.doi.org/10.1155/2022/6732972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865978/
https://www.ncbi.nlm.nih.gov/pubmed/35222802
http://dx.doi.org/10.1155/2022/6732972

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