LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms

Fibroblasts mediate tissue remodeling in eosinophilic esophagitis (EoE), a chronic allergen-driven inflammatory pathology. Diverse fibroblast subtypes with homeostasis-regulating or inflammatory profiles have been recognized in various tissues, but which mediators induce these alternate differentiat...

Descripción completa

Detalles Bibliográficos
Autores principales: Manresa, Mario C., Wu, Amanda, Nhu, Quan M., Chiang, Austin W. T., Okamoto, Kevin, Miki, Haruka, Kurten, Richard, Pham, Elaine, Duong, Loan D., Lewis, Nathan E., Akuthota, Praveen, Croft, Michael, Aceves, Seema S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866113/
https://www.ncbi.nlm.nih.gov/pubmed/34903876
http://dx.doi.org/10.1038/s41385-021-00472-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866113/
https://www.ncbi.nlm.nih.gov/pubmed/34903876
http://dx.doi.org/10.1038/s41385-021-00472-w

Ejemplares similares