MPTAC links alkylation damage signaling to sterol biosynthesis

Overproduction of reactive oxygen species (ROS) drives inflammation and mutagenesis. However, the role of the DNA damage response in immune responses remains largely unknown. Here we found that stabilization of the mismatch repair (MMR) protein MSH6 in response to alkylation damage requires interact...

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Detalles Bibliográficos
Autores principales: Suganuma, Tamaki, Workman, Jerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866156/
https://www.ncbi.nlm.nih.gov/pubmed/35189552
http://dx.doi.org/10.1016/j.redox.2022.102270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8866156/
https://www.ncbi.nlm.nih.gov/pubmed/35189552
http://dx.doi.org/10.1016/j.redox.2022.102270

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